Peptide Academy

The peptide library.

52 compounds — how they work, what the human evidence shows, and where each stands with the FDA. Written for patients, checked against Dr. Laeeq’s clinical references.

Educational reference, not a prescription. Many compounds below are investigational, not FDA-approved, or restricted from compounding; several changed status during 2026. Never self-administer research-grade products. Dosing is shared only with established patients after evaluation. Medical disclaimer

FDA status:52 compounds

Evidence scale: 1 = Preclinical / anecdotal · 2 = Animal data, minimal human · 3 = Limited human data · 4 = Human RCTs or approved abroad · 5 = FDA-approved / large RCTs.

Wondering which, if any, fits you?

Start with an evaluation and labs. Dr. Laeeq will walk you through the evidence for your situation — including when the answer is no.

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The peptide library.

1-DHEA (3-Desoxy DHEA)Oral prohormone that converts to 1-testosterone; gains in lean mass come with lipid, liver and hormonal suppression risks and legal restrictions.Anabolic & AndrogenicRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

5-Amino-1MQOral NNMT inhibitor that raised NAD+ and shrank fat cells in obese mice; promising mechanism but no human studies.Metabolic ModulatorsRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

AmlexanoxOld canker-sore and asthma drug that blocks inflammatory kinases in fat and liver; small human trials suggest benefit in some diabetics.Metabolic ModulatorsApproved · other useEvidence level 3 of 5: Limited human dataEvidence 3/5

AMT (Alpha-MSH)The body's natural tanning and anti-inflammatory melanocortin hormone; parent of afamelanotide, Melanotan II and PT-141.Melanocortin SystemInvestigationalEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

AniracetamFat-soluble racetam that positively modulates AMPA receptors; modest evidence in dementia, unapproved in the U.S.Cognitive & NeuroprotectiveRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

AOD-9604Growth hormone fragment designed to keep GH's fat-burning signal without its effects on blood sugar or IGF-1; human results were modest.Growth Hormone AxisRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

AOD-9604 + Hyaluronic AcidJoint injection pairing hyaluronic acid's lubrication with AOD-9604's proposed cartilage-protective signaling; supported mainly by animal data.Tissue Repair & Anti-InflammatoryRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

BPC-157Gastric-derived 15-amino-acid peptide with strong animal data for tendon, muscle and gut healing; human evidence is minimal.Tissue Repair & Anti-InflammatoryRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

CerebrolysinPorcine brain–derived neurotrophic peptide mixture approved abroad for stroke, dementia and TBI; modest, mixed human trial results.Cognitive & NeuroprotectiveInvestigationalEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

CJC-1295GHRH analog that prompts the pituitary to release more of its own growth hormone; often paired with ipamorelin, but human data are early-stage.Growth Hormone AxisRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

DHH-BMagnolia-derived GABA-A modulator marketed for calm and sleep without next-day grogginess; human evidence is essentially absent.Sleep, Stress & LongevitySupplementEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

DihexaAngiotensin IV–derived oral research compound that boosts HGF/c-Met signaling and synapse formation in animals; no human trials.Cognitive & NeuroprotectiveRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

DSIPBrain-derived peptide studied for deeper sleep, stress buffering and withdrawal; human sleep effects are modest and inconsistent.Sleep, Stress & LongevityRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

EnclomipheneOral SERM that restarts the body's own testosterone production by raising LH and FSH, while preserving fertility, unlike TRT.HPG Axis & ReproductiveInvestigationalEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

EpitalonPineal-derived tetrapeptide studied for telomerase activation, melatonin rhythm and longevity — intriguing data, mostly from one research school.Sleep, Stress & LongevityInvestigationalEvidence level 3 of 5: Limited human dataEvidence 3/5

FGL(L) (FG Loop Peptide)NCAM-derived research peptide that partially activates FGFR1 to support memory and neuroprotection in animal models.Cognitive & NeuroprotectiveInvestigationalEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

GHK-CuCopper-binding tripeptide that supports collagen, wound repair and hair follicles; well established topically, far less so by injection.Cosmetic & TopicalInvestigationalEvidence level 3 of 5: Limited human dataEvidence 3/5

Glycyrrhetinic Acid + Aminophylline CreamCompounded cream combining a lipolysis promoter and a local cortisol blocker for modest spot fat reduction alongside a calorie deficit.Cosmetic & TopicalApproved · other useEvidence level 3 of 5: Limited human dataEvidence 3/5

IGF-1 LR3Long-acting IGF-1 analog with potent anabolic effects in animals; no human trials and significant hypoglycemia and growth-promotion risks.Growth Hormone AxisRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

IpamorelinSelective growth hormone secretagogue that triggers a GH pulse with little effect on cortisol, prolactin or appetite.Growth Hormone AxisRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

iRGDTumor-penetrating peptide that opens a transport route into solid tumors so co-given chemotherapy reaches deeper — investigational, oncology-only.Oncology & SpecializedInvestigationalEvidence level 3 of 5: Limited human dataEvidence 3/5

Kisspeptin-10The most upstream signal of the reproductive axis — triggers GnRH and LH release; studied for hypogonadism, fertility and sexual desire.HPG Axis & ReproductiveRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

KPVAnti-inflammatory tripeptide from α-MSH that calms gut and skin inflammation in animals without tanning effects.Tissue Repair & Anti-InflammatoryRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

Leuphasyl (Pentapeptide-18)Topical enkephalin-mimicking peptide that may soften expression lines modestly — a gentle, much weaker alternative to Botox.Cosmetic & TopicalCosmetic ingredientEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

LGD-4033 (Ligandrol)Oral SARM that builds lean mass in small trials but suppresses natural testosterone, lowers HDL, and has case reports of liver injury.Anabolic & AndrogenicRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

LL-37 (Cathelicidin)The body's own vitamin D–driven antimicrobial peptide; studied topically for wounds, used off-label for biofilm infections.Tissue Repair & Anti-InflammatoryRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

Melanotan IIUnapproved synthetic tanning peptide that also boosts libido and suppresses appetite; notable nausea, BP and mole risks.Melanocortin SystemRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

Met-Enkephalin (OGF)Natural opioid peptide that slows cell proliferation via the OGF receptor; studied as a cancer and immune modulator, closely linked to low-dose naltrexone.Oncology & SpecializedInvestigationalEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

MK-677 (Ibutamoren)Oral ghrelin mimetic that raises GH and IGF-1 for 24 hours; well studied in humans, with appetite and blood-sugar trade-offs.Growth Hormone AxisInvestigationalEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

MOTS-cMitochondria-encoded peptide that activates AMPK and acts like an 'exercise signal' in animals; human data are early.Metabolic ModulatorsRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

Myristoyl Pentapeptide-17Cosmetic lipopeptide in lash and brow serums that supports keratin production; gentle but slower and weaker than prescription bimatoprost.Cosmetic & TopicalCosmetic ingredientEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

NMNNAD+ precursor that reliably raises NAD+ levels in humans; clinical benefits so far are modest and inconsistent.Metabolic ModulatorsSupplementEvidence level 3 of 5: Limited human dataEvidence 3/5

PEG-MGFPegylated fragment of the IGF-1 variant muscle makes after loading; preclinical only, with unresolved questions about whether it works.Growth Hormone AxisRestrictedEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

Pentosan Polysulfate Sodium (PPS)FDA-approved oral IC drug (Elmiron) also used off-label by injection for osteoarthritis; long-term oral use can harm the retina.Tissue Repair & Anti-InflammatoryFDA approvedEvidence level 5 of 5: FDA-approved / large RCTsEvidence 5/5

PNC-27Experimental peptide designed to punch holes in cancer cells that display HDM-2; preclinical only, and subject to an FDA consumer warning.Oncology & SpecializedRestrictedEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

PT-141 (Bremelanotide)FDA-approved (Vyleesi) on-demand melanocortin injection that boosts sexual desire by acting in the brain; nausea is common.Melanocortin SystemFDA approvedEvidence level 5 of 5: FDA-approved / large RCTsEvidence 5/5

PTD-DBMResearch peptide that releases a brake on Wnt signaling to reawaken hair follicles; promising in mice, unproven in people.Cosmetic & TopicalInvestigationalEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

RG3 + Methylcobalamin + NAD+Clinic-compounded cognitive stack pairing an 'RG3' component with B12 and NAD+; components vary and the combo is unstudied.Cognitive & NeuroprotectiveInvestigationalEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

SelankRussian-developed tuftsin analog used intranasally for anxiety and focus; small human studies, approved in Russia only.Cognitive & NeuroprotectiveInvestigationalEvidence level 3 of 5: Limited human dataEvidence 3/5

SemaglutideWeekly GLP-1 agonist with landmark evidence for weight loss, diabetes and heart protection; muscle preservation needs deliberate attention.Metabolic ModulatorsFDA approvedEvidence level 5 of 5: FDA-approved / large RCTsEvidence 5/5

SemaxRussian ACTH-derived nasal peptide that raises BDNF; studied for stroke recovery and focus, with small human trials.Cognitive & NeuroprotectiveRestrictedEvidence level 3 of 5: Limited human dataEvidence 3/5

SermorelinThe original GHRH-fragment peptide, formerly FDA-approved for children, now compounded to restore more youthful GH pulses in adults.Growth Hormone AxisApproved · other useEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

SLU-PP-332Experimental 'exercise mimetic' that switches on mitochondrial energy genes in mice; no human studies yet.Metabolic ModulatorsRestrictedEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

SS-31 (Elamipretide)Mitochondria-targeted peptide that stabilizes cardiolipin in the inner membrane; FDA-approved for Barth syndrome, experimental elsewhere.Metabolic ModulatorsFDA approvedEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

TB-500 / Thymosin Beta-4Thymosin beta-4 fragment that promotes cell migration and angiogenesis; strong animal repair data, no human trials of TB-500.Tissue Repair & Anti-InflammatoryRestrictedEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

TesamorelinFDA-approved GHRH analog with the strongest human evidence of any GH-axis peptide for reducing visceral (organ) fat.Growth Hormone AxisFDA approvedEvidence level 5 of 5: FDA-approved / large RCTsEvidence 5/5

TesofensineOral appetite suppressant that blocks reuptake of three brain neurotransmitters; strong weight-loss trials, but raises heart rate and blood pressure.Metabolic ModulatorsInvestigationalEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

Thymosin Alpha-1Thymic peptide that boosts T-cell and dendritic-cell function; approved abroad (Zadaxin) for hepatitis B, not FDA-approved.Tissue Repair & Anti-InflammatoryInvestigationalEvidence level 4 of 5: Human RCTs or approved abroadEvidence 4/5

TirzepatideWeekly dual GIP/GLP-1 agonist producing the largest average weight loss of approved obesity drugs; lean-mass protection still matters.Metabolic ModulatorsFDA approvedEvidence level 5 of 5: FDA-approved / large RCTsEvidence 5/5

TTA (Tetradecylthioacetic Acid)Modified fatty acid that activates PPAR receptors to increase fat burning; strong in rodents, thin and mixed in humans.Metabolic ModulatorsSupplementEvidence level 2 of 5: Animal data, minimal humanEvidence 2/5

VIPPotent anti-inflammatory neuropeptide used intranasally in CIRS (mold illness) protocols; small human studies only.Tissue Repair & Anti-InflammatoryInvestigationalEvidence level 3 of 5: Limited human dataEvidence 3/5

Zinc ThymulinZinc-dependent thymic hormone used topically for thinning hair; immune biology is real, but human hair-growth evidence is weak.Cosmetic & TopicalInvestigationalEvidence level 1 of 5: Preclinical / anecdotalEvidence 1/5

Wondering which, if any, fits you?